%0 Journal Article
%T Variant CD44 expression is enriching for a cell population with cancer stem cell-like characteristics in human lung adenocarcinoma
%A Ahmed E. Hegab
%A Daisuke Arai
%A Hideyuki Saya
%A Hiroyuki Yasuda
%A Junko Hamamoto
%A Katsuhiko Naoki
%A Kenzo Soejima
%A Makoto Nishino
%A Mari Ozaki
%A Shizuko Kagawa
%A Tomoko Betsuyaku
%J Journal of Cancer
%D 2017
%I Ivyspring International Publisher
%R 10.7150/jca.19732
%X Background: Preliminary studies have identified cancer stem cells (CSCs) in various cancers and there are several ongoing clinical studies targeting these cells. CD44 (standard or variant isoforms) and/or aldehyde dehydrogenase (ALDH) expression is the most commonly used markers for the identification of CSCs. The goal of the current study was to examine the ability of CD44v, either alone or in combination with ALDH, to identify CSCs within human lung cancer cells lines.
%U http://www.jcancer.org/v08p1774.htm