%0 Journal Article %T Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis %A Christian Jorgensen %A Dani¨¨le No£żl %A Karine Toupet %A Marie Maumus %A Olivier Blanc-Brude %A Patricia Luz-Crawford %A Stella Cosenza %J Theranostics %D 2018 %I Ivyspring International Publisher %R 10.7150/thno.21072 %X Objectives: Mesenchymal stem cells (MSCs) release extracellular vesicles (EVs) that display a therapeutic effect in inflammatory disease models. Although MSCs can prevent arthritis, the role of MSCs-derived EVs has never been reported in rheumatoid arthritis. This prompted us to compare the function of exosomes (Exos) and microparticles (MPs) isolated from MSCs and investigate their immunomodulatory function in arthritis. %K mesenchymal stem cells %K extracellular vesicles %K trophic factors %K cell therapy %K rheumatoid arthritis %U http://www.thno.org/v08p1399.htm