%0 Journal Article
%T PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways
%A Bo Jia
%A Chu Chu
%A Dakuan Gao
%A Huadong Zhao
%A Jintao Gu
%A Kuo Zhang
%A Lei Shang
%A Li Gong
%A Nan Mu
%A Nannan Liu
%A Qingdong Guo
%A Tonglie Huang
%A Wangqian Zhang
%A Wei Zhang
%A Xiaochang Xue
%A Zhen Shu
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.22699
%X Purpose: Glioblastoma is the most common and aggressive type of primary brain malignancy and is associated with a poor prognosis. Previously, we found that phosphatase of regenerating liver-3 (PRL-3) was significantly up-regulated in glioblastoma as determined by a microarray analysis. However, the function of PRL-3 in glioblastoma remains unknown. We aimed to investigate the clinical relationship between PRL-3 and glioblastoma, and uncover the mechanisms of PRL-3 in the process of glioblastoma.
%K PRL-3
%K glioblastoma
%K poor prognosis
%K prognostic marker
%U http://www.thno.org/v08p1527.htm