%0 Journal Article
%T Cell-cycle-specific Cellular Responses to Sonoporation
%A Chenliang Cai
%A Dong Zhang
%A Dongxin Yang
%A Juan Tu
%A Junru Wu
%A Lawrence A. Crum
%A Maochen Wang
%A Pengfei Fan
%A Xiasheng Guo
%A Yi Zhang
%A Yiran Li
%J Theranostics
%D 2017
%I Ivyspring International Publisher
%R 10.7150/thno.20820
%X Microbubble-mediated sonoporation has shown its great potential in facilitating intracellular uptake of gene/drugs and other therapeutic agents that are otherwise difficult to enter cells. However, the biophysical mechanisms underlying microbubble-cell interactions remain unclear. Particularly, it is still a major challenge to get a comprehensive understanding of the impact of cell cycle phase on the cellular responses simultaneously occurring in cell membrane and cytoskeleton induced by microbubble sonoporation.
%K Microbubble-mediated sonoporation
%K cell cycle
%K membrane permeabilization
%K cytoskeleton disassembly
%K bubble-cell-interaction
%U http://www.thno.org/v07p4894.htm