%0 Journal Article
%T Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation
%A Alexander D. Borowsky
%A Arta M. Monjazeb
%A Asaf Ilovitsh
%A Brett Z. Fite
%A Clifford G. Tepper
%A Elizabeth S. Ingham
%A Katherine W. Ferrara
%A Lisa M. Mahakian
%A Matthew T. Silvestrini
%A Michael Chavez
%A Neil E. Hubbard
%A Ryan R. Davis
%A Sarah M. Tam
%A William J. Murphy
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.25613
%X Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the enhanced response obtained by combinatorial treatments.
%K ablation
%K RNA sequencing
%K immunotherapy
%K T-cell receptor sequencing
%K ultrasound
%U http://www.thno.org/v08p3611.htm