%0 Journal Article
%T Development of a novel peptide aptamer-based immunoassay to detect Zika virus in serum and urine
%A Do Thi Hoang Kim
%A Duong Tuan Bao
%A Hyun Park
%A Nguyen Minh Ngoc
%A Seon-Ju Yeo
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.25955
%X Zika virus (ZIKV) has been identified as a cause of adverse outcomes of pregnancy, including microcephaly and other congenital diseases. Most people infected with ZIKV do not show any symptoms. Development of a method to discriminate dengue virus (DENV) and ZIKV infections has been challenging, and efficient assays for patient management are limited, attributable to high levels of cross-reactivity among co-circulating Flaviviruses. Thus, there is an urgent need for a specific high-throughput diagnostic assay to discriminate ZIKV infections from other Flavivirus infections.
%K Zika virus
%K peptide aptamer
%K immunoassay
%K serum
%K urine
%U http://www.thno.org/v08p3629.htm