%0 Journal Article
%T MZF-1/Elk-1/PKC¦Į is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
%A Chia-Jen Lee
%A Hsin-ling Yang
%A Je-Chiuan Ye
%A Jen-Hsiang Tsai
%A Jer-Yuh Liu
%A Jin-Ming Hwang
%A Li-Sung Hsu
%A Meen-Woon Hsiao
%J Journal of Cancer
%D 2017
%I Ivyspring International Publisher
%R 10.7150/jca.20467
%X Background: Protein kinase C alpha (PKC¦Į) is a key signaling molecule in human cancer development. As a therapeutic strategy, targeting PKC¦Į is difficult because the molecule is ubiquitously expressed in non-malignant cells. PKC¦Į is regulated by the cooperative interaction of the transcription factors myeloid zinc finger 1 (MZF-1) and Ets-like protein-1 (Elk-1) in human cancer cells.
%K MZF-1
%K Elk-1
%K PKC¦Į
%K HCC.
%U http://www.jcancer.org/v08p3028.htm