%0 Journal Article
%T DNA nanotriangle-scaffolded activatable aptamer probe with ultralow background and robust stability for cancer theranostics
%A Dinggeng He
%A Hui Shi
%A Jinlu Tang
%A Kemin Wang
%A Lv'an Yan
%A Xiaosheng Ye
%A Xiaoxiao He
%A Yanli Lei
%A Zhenzhen Qiao
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.24683
%X Activatable aptamers have emerged as promising molecular tools for cancer theranostics, but reported monovalent activatable aptamer probes remain problematic due to their unsatisfactory affinity and poor stability. To address this problem, we designed a novel theranostic strategy of DNA nanotriangle-scaffolded multivalent split activatable aptamer probe (NTri-SAAP), which combines advantages of programmable self-assembly, multivalent effect and target-activatable architecture.
%K DNA self-assembly
%K multivalent effect
%K activatable imaging
%K split aptamer
%K cancer theranostics
%U http://www.thno.org/v08p4062.htm