%0 Journal Article
%T Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles
%A Aaron Schwartz-Duval
%A Agata Ploska
%A Anna Siekierzycka
%A Christian J. Konopka
%A Dipanjan Pan
%A Gnanasekar Munirathinam
%A Iwona T. Dobrucki
%A Jamila Hedhli
%A Lawrence W. Dobrucki
%A Leszek Kalinowski
%A Marcin Wozniak
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.24791
%X The receptor for advanced glycation end-products (RAGE) is central to multiple disease states, including diabetes-related conditions such as peripheral arterial disease (PAD). Despite RAGE's importance in these pathologies, there remains a need for a molecular imaging agent that can accurately assess RAGE levels in vivo. Therefore, we have developed a multimodal nanoparticle-based imaging agent targeted at RAGE with the well-characterized RAGE ligand, carboxymethyllysine (CML)-modified human serum albumin (HSA).
%K receptor for advanced glycation end-products
%K PET-CT
%K hindlimb ischemia
%K multimodal imaging
%K inflammation
%U http://www.thno.org/v08p5012.htm