%0 Journal Article
%T rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-¦Á Signaling Pathway
%A Beibei Zhang
%A Datao Lin
%A Hui Xie
%A Lian Xu
%A Lifu Wang
%A Qi Liao
%A Shuo Wan
%A Xi Sun
%A Zhiyue Lv
%A Zhongdao Wu
%A Zilong Yu
%J Theranostics
%D 2017
%I Ivyspring International Publisher
%R 10.7150/thno.20359
%X Background: Epidemiologic studies and animal model experiments have shown that parasites have significant modulatory effects on autoimmune disorders, including inflammatory bowel disease (IBD). Recombinant Sj16 (rSj16), a 16-kDa secreted protein of Schistosoma japonicum (S.japonicum) produced by Escherichia coli (E. coli), has been shown to have immunoregulatory effects in vivo and in vitro. In this study, we aimed to determine the effects of rSj16 on dextran sulfate sodium (DSS)-induced colitis.
%K parasites
%K rSj16
%K inflammatory bowel disease
%K protective effects
%K PPAR-¦Á.
%U http://www.thno.org/v07p3446.htm