%0 Journal Article
%T Tumor-specific activated photodynamic therapy with an oxidation-regulated strategy for enhancing anti-tumor efficacy
%A Bowen Liu
%A Feng Feng
%A Huan Liang
%A Mangmang Sang
%A Minjie Sun
%A Renjie Luo
%A Wei Qu
%A Wenyuan Liu
%A Zhanwei Zhou
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.28344
%X Photodynamic therapy relies on photosensitizers to generate cytotoxic reactive oxygen species (ROS) resulting in the apoptois of tumor cells. However, there is an antioxidant system that impedes the elevation of oxidation levels in tumor cells. Thus, photodynamic therapy may exhibit insufficient curative effects due to ungenerous reactive oxygen species levels. Herein, we describe tumor-specific activated photodynamic therapy using an oxidation-regulating strategy.
%K chlorin e6
%K gambogic acid
%K photodynamic therapy
%K ROS-sensitive
%K GSH depletion
%U http://www.thno.org/v08p5059.htm