%0 Journal Article
%T Two-stage oxygen delivery for enhanced radiotherapy by perfluorocarbon nanoparticles
%A Ahu Yuan
%A Baoli Zhang
%A Haoran Wang
%A Jinhui Wu
%A Yiqiao Hu
%A Zaigang Zhou
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.27598
%X Tumors are usually hypoxic, which limits the efficacy of current tumor therapies, especially radiotherapy in which oxygen is essential to promote radiation-induced cell damage. Herein, by taking advantage of the ability of perfluorocarbon (PFC) to promote red blood cell penetration, we developed a simple but effective two-stage oxygen delivery strategy to modulate the hypoxic tumor microenvironment using PFC nanoparticles.
%K perfluorocarbon nanoparticles
%K tumor hypoxia
%K two-stage oxygen delivery
%K radiotherapy
%U http://www.thno.org/v08p4898.htm