%0 Journal Article
%T Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface
%A Chengtie Wu
%A Chun Feng
%A Cuijun Deng
%A Huiying Zhu
%A Jiang Chang
%A Jiayi Li
%A Liming Wang
%A Qingqiang Yao
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.23674
%X The cartilage lesion resulting from osteoarthritis (OA) always extends into subchondral bone. It is of great importance for simultaneous regeneration of two tissues of cartilage and subchondral bone. 3D-printed Sr5(PO4)2SiO4 (SPS) bioactive ceramic scaffolds may achieve the aim of regenerating both of cartilage and subchondral bone. We hypothesized that strontium (Sr) and silicon (Si) ions released from SPS scaffolds play a crucial role in osteochondral defect reconstruction.
%K 3D-printing
%K strontium
%K osteoarthritis
%K osteochondral defects
%K cartilage regeneration.
%U http://www.thno.org/v08p1940.htm