%0 Journal Article
%T The Use of PET Imaging for Prognostic Integrin ¦Á2¦Â1 Phenotyping to Detect Non-Small Cell Lung Cancer and Monitor Drug Resistance Responses
%A Chiun-Wei Huang
%A Chung-Pu Wu
%A Feng-Ting Huang
%A Han Chiu
%A Shih-Ting Hsu
%A Tzu-Chen Yen
%A Wen-Chi Chang
%A Wen-Chuan Hsieh
%A Yi-Hsiu Chung
%A Yi-Wen Lin
%A Yun Han Lin
%J Theranostics
%D 2017
%I Ivyspring International Publisher
%R 10.7150/thno.19304
%X PURPOSE: Growing evidence has demonstrated that aberrant expression of integrin ¦Á2¦Â1 might contribute to the invasion, metastasis and drug resistance of non-small cell lung cancer (NSCLC). Thus, the integrin ¦Á2¦Â1 targeting 68Ga-DOTA-A2B1 tracer was validated in NSCLC in contrast to accumulation of the clinically used 18F-FDG PET tracer to see if 68Ga-DOTA-A2B1-PET imaging can offer a valuable and critical diagnostic imaging criterion for the identification of phenotypes of aggressive lung cancer.
%K Integrin ¦Á2¦Â1
%K Positron emission tomography
%K Non-small cell lung cancer
%K Phenotyping imaging
%K Treatment response monitoring.
%U http://www.thno.org/v07p4013.htm