%0 Journal Article
%T Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma
%A Haiyang Xie
%A Hangxiang Wang
%A Jialin Liu
%A Jiaping Wu
%A Ke Xie
%A Lin Zhou
%A Liqian Zhou
%A Penghong Song
%A Shusen Zheng
%A Xiao Xu
%A Youqing Shen
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.26161
%X Nanomedicines have been extensively explored for cancer treatment, and their efficacies have arguably been proven in various cancer cell-derived xenograft (CDX) mouse models. However, they generally fail to show such therapeutic advantages in patients because of the huge pathological differences between human tumors and CDX models.
%K cancer nanomedicine
%K polylactide
%K SN38 prodrug
%K self-assembly
%K patient-derived xenograft model
%U http://www.thno.org/v08p3949.htm