%0 Journal Article
%T Wnt3a Expression Is Associated with Epithelial-Mesenchymal Transition and Impacts Prognosis of Lung Adenocarcinoma Patients
%A Jian Hu
%A Jinlin Cao
%A Jinming Xu
%A Luming Wang
%A Wang Lv
%A Yeji Hu
%A Yiqing Wang
%J Journal of Cancer
%D 2017
%I Ivyspring International Publisher
%R 10.7150/jca.18560
%X Background: Epithelial-mesenchymal transition (EMT) plays an important role in the invasion and migration during cancer metastasis. Wnt3a is one of the ligands in canonical Wnt/¦Â-catenin signaling pathway, which contributes to the carcinogenesis and progression of lung cancer cell lines. The aim of this study was to evaluate the association between Wnt3a and EMT-related proteins (E-cadherin and N-cadherin), and to further investigate its impact on prognosis of lung adenocarcinoma patients.
%K Wnt3a expression
%K lung adenocarcinoma
%U http://www.jcancer.org/v08p2523.htm