%0 Journal Article
%T Identification of A Panel of Serum microRNAs as Biomarkers for Early Detection of Lung Adenocarcinoma
%A Chuanyong Wu
%A Jian Xue
%A Jiatao Lou
%A Jing Wu
%A Lin Wang
%A Shaogang Lv
%A Shujun Xu
%A Xiaohui Liang
%J Journal of Cancer
%D 2017
%I Ivyspring International Publisher
%R 10.7150/jca.16644
%X Introduction: Since currently no sensitive and specific biomarkers for early detection of lung adenocarcinoma (AD) exist and the majority of AD patients are diagnosed at late stages of disease, the development of effective screening tests for early-stage lung AD is urgently needed. Serum microRNAs (miRNAs) have been documented as novel noninvasive biomarkers in tumor diagnosis; thus, we studied the profile of serum miRNA in AD patients in order to identify the differentially expressed miRNAs as potential biomarkers for early detection of AD.
%K Screening - Low-density array - Receiver operating characteristic (ROC) curve - Area under the ROC curve (AUC) - Logistic regression.
%U http://www.jcancer.org/v08p0048.htm