%0 Journal Article
%T Effects of ¦Á-Mangostin on Viability, Growth and Cohesion of Multicellular Spheroids Derived from Human Breast Cancer Cell Lines
%A Carlo Guarnieri
%A Claudia Pazzini
%A Claudio Muscari
%A Francesca Bonaf¨¨
%A Giuseppe Scolamiero
%J International Journal of Medical Sciences
%D 2018
%R 10.7150/ijms.22002
%X Background: ¦Á-Mangostin (¦ÁMG) is extracted from Garcinia mangostana Linn and exerts antiproliferative activities. Although several researches on ¦ÁMG were performed using cell monolayers, the in vitro pharmacological effects on 3D cancer models have never been investigated. Aim of the present study was to find new anticancer properties of ¦ÁMG by evaluating the changes that this compound provokes in multicellular tumour spheroids (MCTSs).
%K ¦Á-mangostin
%K multicellular tumour spheroid
%K breast cancer
%K cell viability
%K cell migration
%K cell aggregation.
%U http://www.medsci.org/v15p0023.htm