%0 Journal Article
%T Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer
%A Hanjun Hao
%A Jianwen Guo
%A Kun Wang
%A Mengmeng Sun
%A Tong Tong
%A Weiping Gao
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.24705
%X Near-infrared (NIR)-absorbing conjugated polymer nanoparticles are interesting for imaging-guided combination therapy, especially for synergistic photothermal therapy and chemotherapy; however, most of them target tumours passively through the enhanced permeability and retention (EPR) effect, leading to low utilization efficiency. To address this problem, we report an active tumour-targeting strategy of tumour-homing chimeric polypeptide-conjugated NIR-absorbing conjugated-polymer nanoparticles as a new class of drug nanocarriers for imaging-guided combination therapy of cancer.
%K tumour targeting
%K nanomedicine
%K polypyrrole
%K photothermal therapy
%K combination therapy
%U http://www.thno.org/v08p2634.htm