%0 Journal Article
%T Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA
%A Abraham S. Moses
%A Adam W. G. Alani
%A Anna St. Lorenz
%A Canan Schumann
%A Daniel L. Marks
%A Duc X. Nguyen
%A Hassan A. Albarqi
%A Katherine Michaelis
%A Leon Wong
%A Mason Norgard
%A Oleh Taratula
%A Olena R. Taratula
%A Stephanie Chan
%A Stephanie Krasnow
%A Tetiana Korzun
%A Xinxia Zhu
%A Yulia Bortnyak
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.27847
%X Muscle atrophy occurs during chronic diseases, resulting in diminished quality of life and compromised treatment outcomes. There is a high demand for therapeutics that increase muscle mass while abrogating the need for special dietary and exercise requirements. Therefore, we developed an efficient nanomedicine approach capable of increasing muscle mass.
%K mRNA
%K polymeric nanoparticles
%K muscle atrophy
%K follistatin
%K activin A
%K myostatin
%U http://www.thno.org/v08p5276.htm