%0 Journal Article
%T Plasma levels of heart failure biomarkers are primarily a reflection of extracardiac production
%A Adriaan A. Voors
%A Alexandre Mebazaa
%A Arnold Piek
%A Cees W.A. van de Kolk
%A Christian Mueller
%A E. Marloes Schouten
%A Herman H.W. Sillj¨¦
%A Rudolf A. de Boer
%A Weijie Du
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.26055
%X Plasma heart failure (HF) biomarkers, like natriuretic peptides, are important in diagnosis, prognosis and HF treatment. Several novel HF biomarkers have been identified, including Gal-3, GDF-15 and TIMP-1, but their clinical potential remains vague. Here we investigated plasma biomarker levels in relation to tissue expression and structural and functional cardiac changes.
%K heart failure
%K cardiac remodeling
%K biomarker
%K Galectin-3
%K GDF-15
%K TIMP-1
%U http://www.thno.org/v08p4155.htm