%0 Journal Article
%T Effect of the oncolytic ECHO-7 virus Rigvir£¿ on the viability of cell lines of human origin in vitro
%A Andra Tilgase
%A Anna Ramata£¿Stunda
%A Ilze Bl¨¡£¿e
%A Liene Patetko
%A M¨¡rti£¿£¿ Borodu£¿£¿is
%A P¨¥teris Alberts
%J Journal of Cancer
%D 2018
%I Ivyspring International Publisher
%R 10.7150/jca.23242
%X Background: The role of oncolytic viruses in cancer treatment is increasingly studied. The first oncolytic virus (Rigvir£¿, ECHO-7) was registered in Latvia over a decade ago. In a recent retrospective study Rigvir£¿ decreased mortality 4.39-6.57-fold in stage IB-IIC melanoma patients. The aims of the present study are to test the effect of Rigvir£¿ on cell line viability in vitro and to visualize the cellular presence of Rigvir£¿ by immunocytochemistry.
%K ECHO-7 virus
%K immunocytochemistry
%K oncolytic virus
%K cell viability
%K Rigvir.
%U http://www.jcancer.org/v09p1033.htm