%0 Journal Article %T 甲状腺功能减退与子宫内膜癌的相关性分析 %A 廖玉萍 %A 杨冰 %J 肿瘤防治研究 %D 2019 %R 10.3971/j.issn.1000-8578.2019.18.1902 %X 摘要 目的 探讨甲状腺功能减退与子宫内膜癌(EC)的关系及EC患者癌组织分化程度和雌激素受体(ER)、孕激素受体(PR)的表达与甲状腺功能之间的关系。方法 选取2015年1月—2018年7月我院收治的EC患者113例,同时随机选取年龄与EC组相匹配的此段时间内我院健康体检的妇女156例作为对照组,检测血清促甲状腺激素(TSH)、甲状腺激素(FT4)。比较两组间甲状腺功能减退的患病率,并利用免疫组织化学法测定EC患者手术切除标本的癌组织中ER、PR的表达,分析EC患者癌组织分化程度及癌组织中ER、PR的表达与甲状腺功能之间的相关性。结果 EC组甲状腺功能减退的患病率较对照组高(P<0.000)。低分化EC患者的TSH高于中分化EC患者(P=0.025)。EC手术切除标本的癌组织中ER、PR阳性与阴性患者的TSH、FT4差异无统计学意义(P>0.05)。结论 甲状腺功能减退与EC具有相关性 %K 目的 探讨甲状腺功能减退与子宫内膜癌(EC)的关系及EC患者癌组织分化程度和雌激素受体(ER)、孕激素受体(PR)的表达与甲状腺功能之间的关系。方法 选取2015年1月—2018年7月我院收治的EC患者113例 %K 同时随机选取年龄与EC组相匹配的此段时间内我院健康体检的妇女156例作为对照组 %K 检测血清促甲状腺激素(TSH)、甲状腺激素(FT4)。比较两组间甲状腺功能减退的患病率 %K 并利用免疫组织化学法测定EC患者手术切除标本的癌组织中ER、PR的表达 %K 分析EC患者癌组织分化程度及癌组织中ER、PR的表达与甲状腺功能之间的相关性。结果 EC组甲状腺功能减退的患病率较对照组高(P<0.000)。低分化EC患者的TSH高于中分化EC患者(P=0.025)。EC手术切除标本的癌组织中ER、PR阳性与阴性患者的TSH、FT4差异无统计学意义(P>0.05)。结论 甲状腺功能减退与EC具有相关性。 %K Blockade of Radiation-induced EGFR Nuclear Transport Enhances Radiosensitivity of Human Cervical Cancer %K Recurrence-related Factors of 46 Stage Ⅰ-Ⅱ Endometrial Carcinoma Patients %K Comparison of Survival and Postoperative Complication of Stage Ⅰb2-Ⅱa2 Cervical Cancer Patients Among Three Kinds of Therapeutic Regimens %K Effects of Pachymaran on Proliferation %K Migration and Pro-apoptosis of Human Cervical Carcinoma HeLa Cells and Its Mechanism %K Clinical Treatment and Prognosis of 101 Patients with Small Cell Neuroendocrine Carcinoma of Cervix %K Expression of Serum miR-1246 in Patients with Cervical Squamous Cell Carcinoma and Its Clinical Significance %K Expression and Correlation of miR-135a-5p %K GATA3 and STAT3 in Cervical Cancer %K Tumor-associated Macrophages Promote Invasion and Metastasis of Cervical Cancer %K Indocyanine Green Angiography for Preserving Ureteral Branch of Uterine Artery in Radical Hysterectomy %K Effect of Overexpression of Follistatin-like Protein 1 on Downstream Genes in Cervical Cancer and Bioinformatic Analysis of Downstream Genes %K Risk Factors of Lymph Node Metastasis in Early-stage Cervical Cancer Patients and Build of A Nomogram Prediction Model %K miR-198 Targets MAPK1 to Regulate Proliferation %K Apoptosis and Invasion of Cervical Cancer HeLa Cells %K δ-tocotrienol Inhibits Proliferation of Cervical Carcinoma Cells Through Upregulating MicroRNA-34a %K Influences of FGF3 and FGF10 on Migration and Invasion of Human Ovarian Cancer SKOV3 Cells and Relation Between These Influences and Wnt/β-catenin Signaling Pathway %K Effect of High Energy X-rays at Different Dose Rates on Biological Effects of Cervical Cancer HeLa Cells %U http://www.zlfzyj.com/CN/abstract/abstract9399.shtml