%0 Journal Article
%T 肿瘤纯度——肿瘤研究中一个被忽视的潜在混杂因素
%A 李岚
%A 查莉审校
%A 许斌综述
%J 肿瘤防治研究
%D 2019
%R 10.3971/j.issn.1000-8578.2019.19.0018
%X 摘要 肿瘤组织中除了肿瘤细胞之外还有免疫细胞、基质细胞、间质细胞等非肿瘤细胞，共同影响肿瘤发生发展。肿瘤纯度与肿瘤患者临床特征、基因组表达和生物学特性显著相关，研究过程中对肿瘤样本进行分析时应充分考虑肿瘤纯度的影响。本文主要从概念、现有的计算方式及对基因组分析的影响三个方面对肿瘤纯度行简要综述
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%U http://www.zlfzyj.com/CN/abstract/abstract9422.shtml