%0 Journal Article %T 肿瘤中SWI/SNF复合物亚基变异的作用及其相关治疗策略进展 %A 周志毅 %A 郭庆 %A 饶秋 %J 肿瘤防治研究 %D 2019 %R 10.3971/j.issn.1000-8578.2019.18.1871 %X 摘要 SWI/SNF复合物是调节真核细胞基因表达的一种重要而复杂的多亚基蛋白复合物,广泛参与信号转导、细胞周期及分化等各种生物过程,其亚基基因在20%以上的恶性肿瘤中发生突变。本文综述了该复合物及其亚基在恶性肿瘤中的作用和特征,并探讨SWI/SNF复合物在肿瘤治疗中的潜在临床应用 %K Advances in Immunotherapy for Malignant Tumors %K Clinicopathological and Prognostic Value of Circulating Tumor Cells in Peripheral Blood in Head and Neck Cancer Patients: A Meta-analysis %K Characteristics of Interhospital Consultation in Cancer Specialized Hospitals %K Research Progress of CD47-SIRPα Signaling Axis as An Innate Immune Checkpoint in Cancer %K Influence of Different Radio-chemotherapy Modes for Incidence of Radiation Pneumonitis in Patients with Lung Cancer %K Pathogenesis of Malignant Tumor with Hypercoagulable State in Traditional Chinese Medicine and Western Medicine %K Research Advances of saRNA in Human Malignant Tumors %K Retrospective Analysis of Hospitalized Patients with Malignant Tumors in Hu’nan Cancer Hospital %K 2007-2016 %U http://www.zlfzyj.com/CN/abstract/abstract9439.shtml