%0 Journal Article
%T 128层双源CT大螺距高心率冠状动脉成像的量化与限度：一项模拟研究<br>Quantification and limitation of CT coronary angiography using 128-slice dual-source CT at high heart rate: A simulation study
%A 赵 磊
%A 郭佑民
%A 郝粉娥
%A 杨晓光
%A 吕铁钢
%A 王泽锋
%A 杨振兴
%A 刘挨师
%J 西安交通大学学报(医学版)
%D 2019
%R 10.7652/jdyxb201902027
%X 摘要：目的 通过小螺距扫描全心动周期重建模拟收缩末期触发大螺距扫描，定量评价收缩末期触发时间窗特征以指导高心率大螺距扫描的临床应用。方法 本研究共选取62例连续患者进行回顾性心电门控全心动周期小螺距扫描。扫描结束后进行图像重建，层厚为0.75mm，层间距为13.75mm，并以时间间隔10ms进行0～700ms拆分，并按0～400ms组合图像以评价收缩末期触发时间窗。结果 入组患者平均心率为(75.52±8.73)次/min，平均收缩末期触发时间窗宽(STTWw)绝对期相为(120.16±75.13)ms，相对期相为(14.70±8.74)%；平均收缩末期触发时间窗位(STTWc)绝对期相为(148.31±51.79)ms，相对期相为(18.24±5.60)%。心率与STTWc相对期相呈负相关(r=-0.306, P=0.016)。心率切点为86次/min(AUC=0.933, P=0.038)。结论 本研究解释和揭示了高心率大螺距CT冠状动脉造影技术特征，明确了其在心率大于80次/min患者应用的局限性。<br>ABSTRACT: Objective To simulate the systolic imaging of high-pitch scan for CT coronary angiography in order to evaluate and analyze the distribution features of systolic triggered temporal window (STTW) for high-pitch scan at high heart rate (HR). Methods Sixty-two consecutive patients were enrolled in our study. Retrospective electrocardiography (ECG) gating low-pitch scan with full cardiac cycle reconstruction was used for all the patients. The reconstruction thickness and gap were 0.75mm and 13.75mm, respectively. The data from 0ms to 700ms after R wave was reconstructed with every 10ms. The STTW would be evaluated from 0ms to 400ms. Results The mean HR was (75.52±8.73)times/min. The STTWwidth (STTWw) was (120.16±75.13)ms for absolute phase and (14.70±8.74)% for relative phase. The STTWcenter (STTWc) was (148.31±51.79)ms for absolute phase and (18.24±5.60)% for relative phase. There was a negative correlation between HR and relative STTWc (r=-0.306, P=0.016). Cut-off value of image assessment was 86bpm (AUC=0.933, P=0.038). Conclusion Our study described the features of STTW, explained the feasibility of routine high-pitch CTCA with end systolic acquisition at high HR, and revealed the values and limitations of high-pitch scan at high HR
%K 体层摄影术
%K 心率
%K 冠心病
%K 冠状动脉成像
%K 辐射剂量<br>computed tomography
%K heart rate
%K coronary artery disease
%K coronary artery imaging
%K radiation dose
%U http://yxxb.xjtu.edu.cn//oa/darticle.aspx?type=view&id=201902027