%0 Journal Article
%T Microangiopathic Hemolytic Anemia: A Rare Clue to Diagnose Bone Marrow Metastatic Gastric Adenocarcinoma
%A Istiuqe Ahmed
%A Md Faizul Islam Chowdhury
%A Md Habibur Rahman
%A Md Kamrul Hasan Patwari
%A Md Shahriar Siddiki
%A Minahj Uddin Bhuiyan
%A Nur Alam
%A Rajib Bhowmic
%A Sarmistha Biswas
%J Journal of Medicine
%D 2019
%R https://doi.org/10.3329/jom.v20i2.42012
%X Microangiopathic Hemolytic Anemia (MAHA) is a hematological condition which is very rare for the primary presentation of a gastric adenocarcinoma with bone marrow metastases. When it emerges as initial findings in a previously undetected case of malignancy, the diagnosis is often missed and results in inappropriate management. Carcinoma stomach associated with MAHA is generally having fulminant course. This is a case report of a 30-year-old male who presented with widespread bone marrow infiltration along with CoombĄ¯s negative haemolytic anemia, thrombocytopenia and schistocytes in peripheral blood typical of MAHA. The combination of MAHA and bone marrow infiltration in gastric adenocarcinoma is a very rare entity. When the cause of progressive MAHA is unknown, the possibility of cancer-associated MAHA must be excluded by performing additional tumor workup, including the detection of tumor markers, Endoscopy of upper GIT, colonoscopy, bone marrow examinations, and PET-CT or bone scans
%U https://www.banglajol.info/index.php/JOM/article/view/42012