%0 Journal Article
%T Effect of Perioperative Administration of Tranexamic Acid on Postoperative Bleeding Following on Pump CABG
%J Cardiovascular Journal
%D 2019
%R https://doi.org/10.3329/cardio.v12i1.43414
%X Background: One of the main causes of post-operative morbidity in cardiac surgical patient is excessive bleeding requiring transfusion of blood component after CPB. Re-exploration due to bleeding occurs in 2% to 7% of post bypass patient and 50% to 80% of these patients not having any identifiable surgical bleeding source. Tranexamic acid is competitive inhibitor of plasminogen activator and at higher concentration a non-competitive inhibitor of plasmin. It is 10 times more potent than Epsilone Aminocaproic Acid in preventing post-operative haemorrhage following CPB
%U https://www.banglajol.info/index.php/CARDIO/article/view/43414