%0 Journal Article
%T What is the Link between Malaria Prevention in Pregnancy and Neonatal Survival in Nigeria?
%A Adeniyi F.
%A Adeoye
%A Ikeola A. & Fagbamigbe
%J African Journal of Reproductive Health
%D 2019
%X Neonatal mortality has been recognized as a global public health challenge and Nigeria has the highest prevalence in Africa. Malaria during pregnancy jeopardizes neonatal survival through placental parasitaemia, maternal anaemia, and low birth weight. This study investigated association between the malaria prevention in pregnancy and neonatal survival using a nationally representative data - Nigeria Demographic Health Survey 2013. Child recode data was used and the outcome variable was neonatal death. The main independent variables were the use of at least 2 doses of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPT-SP) and proportion of pregnant women who reported Insecticide Treated Net (ITN) use the night before the survey. Data were analyzed using Pearson Chi-square ( x2) test of association and survival analysis techniques. Total neonatal mortality rate was 38 per1000 live births. Cox proportional hazard model showed that low birth weight (HR 1.49, 95% CI (1.15 ¨C 1.93 p=0.003) and adequate number of ANC visits (¡Ý 4 visits) (HR 0.68, 95% CI (0.53 ¨C 0.93) were associated with neonatal survival. The use of at least 2 doses of IPT-SP was not an independent factor for neonatal survival (HR 0.72, 95% CI (0.53 ¨C 1.15). Malaria prevention in pregnancy is crucial for neonatal survival through the prevention of low birth weight. (Afr J Reprod Health 2019; 23[1]: 139-149). La mortalit¨¦ n¨¦onatale a ¨¦t¨¦ reconnue comme un probl¨¨me de sant¨¦ publique mondial et le Nig¨¦ria connait la pr¨¦valence la plus ¨¦lev¨¦e d'Afrique. Le paludisme pendant la grossesse compromet la survie n¨¦onatale par la parasit¨¦mie placentaire, l'an¨¦mie maternelle et l'insuffisance pond¨¦rale ¨¤ la naissance. Cette ¨¦tude a examin¨¦ l'association entre la pr¨¦vention du paludisme pendant la grossesse et la survie n¨¦onatale ¨¤ l'aide de donn¨¦es repr¨¦sentatives au niveau national - Enqu¨ºte d¨¦mographique sur la sant¨¦ au Nig¨¦ria de 2013. Les donn¨¦es de recodage des enfants ont ¨¦t¨¦ utilis¨¦es. Les principales variables ind¨¦pendantes ¨¦taient l'utilisation d'au moins 2 doses de traitement pr¨¦ventif intermittent pendant la grossesse par la sulfadoxine-pyrim¨¦thamine (IPT-SP) et la proportion de femmes enceintes qui avaient d¨¦clar¨¦ avoir utilis¨¦ une moustiquaire impr¨¦gn¨¦e d'insecticide (MII) la nuit pr¨¦c¨¦dant l'enqu¨ºte. Les donn¨¦es ont ¨¦t¨¦ analys¨¦es ¨¤ l'aide du test de Pearson sur le chi carr¨¦ (x 2) des techniques d'analyse d'association et de survie. Le taux de mortalit¨¦ n¨¦onatale total ¨¦tait de 38 pour 1 000 naissances vivantes. Le mod¨¨le de risque proportionnel de Cox a montr¨¦
%U http://www.bioline.org.br/abstract?id=rh19014&lang=en