%0 Journal Article
%T Serum Aspartic Acid £¿as a Marker of Epilepsy | AlGawwam | Global Journal of Health Science | CCSE
%A Akram Al-Mahdawi
%A Asaad Adil Mnaather
%A Gheyath AlGawwam
%A Hayder A. Fawzi
%A Laith G. £¿ Shareef
%J Home | Global Journal of Health Science | CCSE
%D 2019
%R 10.5539/gjhs.v11n2p142
%X OBJECTIVE: Determine the £¿diagnostic validity of serum aspartic acid as a predictor of epilepsy.

STUDY DESIGN & METHODOLOGY: This study enrolled 80 epileptic patients and 80 healthy people, and we measure serum level of £¿aspartic acid by using high liquid performance chromatography.

RESULTS: Mean serum aspartic acid £¿was significantly higher in patients (26.2 ¡À 10.1) mg\dl while in control was (2.8 ¡À 1.36) mg\dl, £¿the result showed that aspartic acid is an excellent predictor area under the curve [AUC] (95%CI) = £¿£¿0.988 (0.97 ¨C 1.0) with 96.3% sensitivity and 97.5% specificity for epileptic patients. Also, the £¿result shows generalized seizure has significantly higher mean serum aspartic acid compared to £¿partial type and GTC show significantly higher mean serum aspartic acid compared to £¿myoclonus.

CONCLUSION: Aspartic acid serum level markedly elevated in epileptic patients £¿groups in comparison to the healthy group, also shows a marked difference between generalized £¿and partial epilepsy and show different levels between subtypes of epilepsy.
%U http://www.ccsenet.org/journal/index.php/gjhs/article/view/0/38277