%0 Journal Article %T Sprue-Like Intestinal Disease Complicated by Inclusion Body Myositis %A Hugh J. Freeman %J International Journal of Celiac Disease %D 2019 %R 10.12691/ijcd-7-2-5 %X A woman with long-standing weight loss and malabsorption demonstrated a severe sprue-like enteropathy. She insidiously developed persistent and progressive muscle weakness caused by inclusion body myositis, an uncommon muscle disorder. Treatment with a gluten-free diet, steroids, calcium, zinc and vitamin supplements, including empirical vitamin E resulted in weight gain, but failed to histologically improve her small intestinal mucosa or the muscle weakness which became profound. The myopathic process could reflect a co-existent autoimmune disorder, or, possibly a direct result of long-standing and superimposed nutrient deficits. An alternative explanation may be a hitherto unrecognized syndrome manifested as inclusion body myositis and a form of sprue-like enteropathy %U http://www.sciepub.com/IJCD/abstract/10819