%0 Journal Article
%T An Undergraduate Experiment Using Cyclodextrin ¨C Assisted Sensitive Fluorescence Detection and Quantitation of Dapsone Drug in Wastewater Samples
%A Abdullah Al-Hemyari
%A Ahmad Alhalabi
%A Mohammed A. Meetani
%A Mohammed K. Al-tabaji
%A Munjed Maraqa
%A Nada Elmari
%A Noor I Albadawi
%A Soleiman Hisaindee
%J World Journal of Chemical Education
%D 2019
%R 10.12691/wjce-7-4-2
%X The guest-host interaction between Dapsone drug and ¦Â-cyclodextrin (¦Â-CD) was investigated using fluorescence spectroscopy, 1H-NMR, and liquid chromatography with fluorescence detection. The optimized conditions for the interaction were investigated by spectrofluorometry and were found to be at 0.2 mg/mL (0.176 mM) of ¦Â-CD and pH 8.8. For these conditions, very low concentration of Dapsone drug of 2.4 ng/mL (12.97 nM) can be detected. The standard addition method was utilized to detect Dapsone in influent and effluent wastewater samples in the sub parts per billion concentration range by HPLC-FLD using ¦Â-CD as an additive in the mobile phase
%U http://www.sciepub.com/WJCE/abstract/10970