%0 Journal Article %T Effects of supra-nutritional levels of vitamin E and vitamin C on growth performance and blood parameters of Japanese quails %A Aldo Pr %A Alireza Seidavi %A Antonio Gallo %A Roshanak Khazaei %A Samantha Sigolo %A Tugay Ayasan %A ini %J Italian Journal of Animal Science %D 2019 %X Abstract A study was conducted to evaluate growth performance and blood serum parameters of Japanese quails fed diets containing different supra-nutritional levels of vitamin E and C (600, 800 and 1000£¿mg/kg). A completely randomised design was adopted and main effects (vitamin E and C) were arranged in a 3£¿¡Á£¿3 factorial approach. Throughout the study (1¨C42 d), the supplementation with 1000£¿mg/kg vitamin E and C resulted in the highest feed intake, weight gain, and final body weight (p£¿<£¿.01). Serum parameters showed that vitamin E and C at 1000£¿mg/kg determined the lowest serum concentrations of glucose, uric acid and creatinine (p£¿¡Ü£¿0.01) and the highest of high (HDL, p£¿=£¿.01) and low (LDL, p£¿=£¿.05) density lipoprotein cholesterol and albumin (p£¿<£¿.01). The administering of 1000£¿mg/kg vitamin E or C reduced triglycerides (p£¿<£¿.01), aspartate amino transferase (E, p£¿<£¿.01; C, p£¿=£¿.02) and alanine amino transferase (E, p£¿<£¿.01; C, p£¿=£¿.01) whereas increased total protein, calcium, phosphorous, thyroid stimulating hormone, red blood cells, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration (p£¿<£¿.01). Vitamin C at 800 or 1000£¿mg/kg level decreased serum total cholesterol (p£¿<£¿.01) whereas vitamin E achieved the lowest alkaline phosphatase and the highest haemoglobin serum concentration (p£¿<£¿.01). The findings showed that these vitamins, used together at 1000£¿mg/kg, can individually or synergistically act promoting quail health, feed intake and growth. Highlights The use of vitamin E and C at high doses (1000£¿mg/kg) in quail diet can promote animal health. The vitamin E and C administration at high levels can be a good management practice in quail nutrition to promote feed intake and growth %U https://www.tandfonline.com/doi/full/10.1080/1828051X.2018.1500496