%0 Journal Article
%T Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates
%A Chen Chen
%A Hongyan Zhang
%A Longhua Xu
%A Ximo Wang
%A Zhixiang Xu
%J Food and Agricultural Immunology
%D 2019
%R https://doi.org/10.1080/09540105.2019.1649371
%X ABSTRACT In this study, a direct competitive molecularly imprinted biomimetic immunoassay method was developed for determination of the plasticizer dibutyl phthalate. Water-soluble carboxyl quantum dots were used as the marker. A hydrophilic molecularly imprinted polymer synthesized directly on the surface of a 96-well plate was used as biomimetic antibody. Under the optimal conditions, the limit of detection and the sensitivity of the method were 0.011 and 0.136£¿mg/L respectively. The cross-reaction values of two structural analogs were 4.75% and 6.89%, this indicaties that the method has the good specificity. Edible oil samples spiked with dibutyl phthalate were assayed, and good recoveries ranging from 80.0% to 111.5% were obtained. The method was used to detect dibutyl phthalate residues in liquors, and there were no significant differences obtained using the developed method and those obtained using gas chromatography
%U https://www.tandfonline.com/doi/full/10.1080/09540105.2019.1649371