%0 Journal Article %T Multi-Mode adhesives performance and success/retention rates in NCCLs restorations: randomised clinical trial one-year report %A Joana Domingues %A Liliana Teixeira %A Maria Concei£¿£¿o Manso %A Patr¨ªcia Manarte-Monteiro %A S %A ra Gavinha %J Biomaterial Investigations in Dentistry %D 2019 %R https://doi.org/10.1080/26415275.2019.1684199 %X Abstract Aim: Compare clinical performance and success/retention rates of two multi-mode (MM) adhesives, applied in self-etch (SE) or etch-and-rinse (ER) modes, with SE-all-in-one adhesive (SE/SE with enamel etching) in NCCL restorations at one-year follow-up. Material and methods: Prospective, double-blind RCT approved by the University Fernando Pessoa and the National-Clinical-Research-Ethics Committees (CEIC-20150305), ClinicalTrials.gov registered (NCT02698371), in 38 participants with 210 restorations (AdmiraFusion£¿) randomly allocated to six groups (Adhesives_Adhesion mode), each with 35 restorations: G1-Control Futurabond£¿DC_SE; G2-Control Futurabond£¿DC_SE with enamel etching; G3-Futurabond£¿U_ER; G4-Futurabond£¿U_SE; G5-Adhese£¿Universal_ER; G6-Adhese£¿Universal_SE. Restorations evaluated at baseline and one-year by three calibrated examiners (ICC ¡Ý0.952) using FDI criteria and statistical analysis with nonparametric tests (alpha = 0.05). Results: At one-year recall 36 participants, 199 restorations were available for examination; five (2.5%) restorations (G1 n£¿=£¿2; G2, G3, G4 n£¿=£¿1) were lost due to retention (p£¿>£¿.05); G1 showed less satisfying marginal adaptation (p£¿<£¿.05) than G2 and MM adhesives groups, particularly G6. Overall success rates (p£¿>£¿.05) were: 93.9% (G1), 97.0% (G2; G3; G4) and 100.0% (G5; G6). Conclusions: MM adhesives (Futurabond£¿U and Adhese£¿Universal) showed similar and acceptable performance/success rates but also better clinical outputs than the SE-all-in-one adhesive (Futurabond£¿DC), particularly in SE mode. Success and retention rates were similar and not dependent on materials or adhesion modes %U https://www.tandfonline.com/doi/full/10.1080/26415275.2019.1684199