%0 Journal Article
%T Creatine or guanidinoacetic acid? Which is more effective at enhancing growth, tissue creatine stores, quality of meat, and genes controlling growth/myogenesis in Mulard ducks
%A A. M. Morshedy
%A Ahmed Abdelfattah-Hassan
%A Doaa Ibrahim
%A Rania El Sayed
%J Journal of Applied Animal Research
%D 2019
%R https://doi.org/10.1080/09712119.2019.1590205
%X ABSTRACT This study aimed to determine the effectiveness of guanidinoacetic acid (GAA) with or without methionine (Met) compared to creatine (CREA) at enhancing duck¡¯s performance, restoring tissue CREA and improving meat quality. Mulard ducklings (n£¿=£¿250) were randomly assigned to control (without additives), or control plus CREA, GAA, GAA£¿+£¿0.2%Met (GAAMet0.2) or GAA£¿+£¿0.4%Met (GAAMet0.4) groups in a completely random experimental design. Dietary supplementation of CREA or GAA significantly increased (P£¿<£¿0.05) overall weight gain and improved feed:gain ratio. Supplementation of GAA (especially GAAMet0.4 group) significantly increased (P£¿<£¿0.05) carcass and breast yield. Meat pH values were higher (P£¿<£¿0.05) with dietary GAA£¿+£¿Met or CREA. Providing of dietary GAA£¿+£¿Met led to higher levels of plasma CREA than dietary CREA itself. The molecular investigation indicated that dietary CREA or GAA with Met enhanced the gene expression of hepatic insulin-like growth factor-1, growth hormone and muscle myogenin. Finally, dietary GAA£¿+£¿Met was superior to CREA in improving duck¡¯s performance based on molecular markers related to growth (IGF-1 and growth hormone) and myogenesis (upregulating myogenin and downregulating myostatin). Although, dietary GAA£¿+£¿Met enhanced muscle¡¯s CREA loading than CREA, the long-term GAA supplementation in ducks may induce methyl-groups shortage for protein synthesis, this was resolved with Met addition in our study
%U https://www.tandfonline.com/doi/full/10.1080/09712119.2019.1590205