%0 Journal Article
%T Efficient one-pot catalyst-free synthesis of novel coumarin- spiro[indoline-3,4'-pyran] conjugates via three-component domino reaction in aqueous medium
%A Adil Omar
%A Keyume Ablajan
%J Green Chemistry Letters and Reviews
%D 2019
%R https://doi.org/10.1080/17518253.2018.1556744
%X ABSTRACT A simple, efficient, eco-friendly and catalyst-free procedure was developed for the construction of novel coumarin-spiro[indoline-3,4'-pyran] conjugates via three-component reactions of various synthetic beta-ketoesters with isatins and malononitrile in aqueous medium. In addition to operational simplicity and absence of tedious separation procedures, being catalyst¨Cfree is the prominent advantage of this method. GRAPHICAL ABSTRAC
%U https://www.tandfonline.com/doi/full/10.1080/17518253.2018.1556744