%0 Journal Article
%T Prevalence of Vitamin D deficiency in a multiracial female population in KwaZulu-Natal province, South Africa
%A Jagidesa Moodley
%A Lorna Madurai
%A Thajasvarie Naicker
%A Yeshnee Naidoo
%J South African Family Practice
%D 2019
%R https://doi.org/10.1080/20786190.2018.1541579
%X Objective: Vitamin D deficiency is a global health issue affecting many countries, especially those in temperate climates. The aim of this study was to determine the prevalence of Vitamin D deficiency and level of 25-hydroxyvitamin D [25(OH)D] in females categorised by age and race. Methods: The study was performed between January 2015 and January 2016. This study consisted of 1 976 females stratified by age into < 18, reproductive age (18¨C45) and > 45 years. Demographic variables were recorded and serum 25(OH)D levels measured by chemiluminescent emission. Results: The predictors of lower 25(OH)D levels included age and race, (p£¿<£¿0.0001 for each predictor). Approximately 46% of females had < 20£¿ng/ml 25(OH)D level, the majority of whom were Indian (35%). The 25(OH)D level varied by race (White 27.33£¿ng/ml; Black 23.43£¿ng/ml and Indian 15.05£¿ng/ml; p£¿<£¿0.0001). In the <18-year age category, White and Black women had significantly higher 25(OH)D levels when compared with Indian women (38.25£¿ng/ml vs. 37.51£¿ng/ml vs. 13.68£¿ng/ml respectively; p£¿<£¿0.0001). Similarly, in the reproductive age category (18¨C45 years); White (27.63£¿ng/ml) and Black (20.93£¿ng/ml) women had a significantly higher 25(OH)D level compared with Indian (13.15£¿ng/ml) women (p£¿<£¿0.0001). Moreover, similar data were observed within the > 45-year age category, where the White and Black women had higher 25(OH)D levels compared with Indian women (25.46£¿ng/ml vs. 22.73£¿ng/ml vs. 17.04£¿ng/ml; p£¿<£¿0.0001) respectively. Irrespective of age category, severe vitamin D deficiency was highest amongst Indian females. Conclusion: This study demonstrates a significant difference in 25(OH)D concentration in healthy females living in Durban, with Indians presenting with the highest vitamin D deficiency. These findings clearly highlight the need for a policy on vitamin D supplementation and/or fortification of food. Further studies are under way to assess the genetic predisposition of women to vitamin D deficiency
%U https://www.tandfonline.com/doi/full/10.1080/20786190.2018.1541579