%0 Journal Article
%T Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai
%A Bin-Gui Wang
%A Hong-Lei Li
%A Ling-Hong Meng
%A Sui-Qun Yang
%A Xiao-Ming Li
%A Xin Li
%J Marine Drugs | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/md17110605
%X Three new prenylated phenol derivatives, terreprenphenols A¨CC (1¨C3), along with four known related compounds (4¨C7), were isolated from Aspergillus terreus EN-539, an endophytic fungus obtained from the marine red alga Laurencia okamurai. The structures of these compounds were established by extensive analysis of 1D/2D NMR data, mass spectrometric data, and optical rotation (OR). The corresponding relationship between absolute configuration and optical rotation for known compounds anodendroic acid (4) and asperterreusine C (5) was ambiguous in literature, and their absolute configurations were therefore discussed and confirmed for the first time by time-dependent density functional (TDDFT) ECD and OR calculations. Compounds 1¨C7 inhibited some common aquatic bacteria with MIC values ranging from 2 to 64 ¦Ìg/mL
%U https://www.mdpi.com/1660-3397/17/11/605