%0 Journal Article
%T Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil
%J Gels | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/gels5010005
%X In this work, we present Thioflavin T fluorescence, transmission electron microscopy (TEM), circular dichroism (CD), Fourier-transformed infrared (FT-IR), and oscillatory rheometry studies applied to an antineoplastic drug, 5-fluorouracil (5-FU), embedded in a heterochiral tripeptide hydrogel to obtain a drug delivery supramolecular system. The release of 5-fluorouracil was monitored over time by reverse-phase high-performance liquid chromatography (HPLC) and its interaction with the tripeptide assemblies was probed by all-atom molecular dynamics simulations. View Full-Tex
%U https://www.mdpi.com/2310-2861/5/1/5