%0 Journal Article
%T Antibacterial Performance of Terpenoids from the Australian Plant Eremophila lucida
%A Chi P. Ndi
%A Hans J. Griesser
%A Israt J. Biva
%A Susan J. Semple
%J Antibiotics | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/antibiotics8020063
%X Plants in the Australian genus Eremophila (Scrophulariaceae) have attracted considerable recent attention for their antimicrobial compounds, which possess a wide range of chemical structures. As they are typically associated with the oily-waxy resin layer covering leaves and green branchlets, and Eremophila lucida is prominent among the species containing a pronounced sticky resin layer, this species was considered of interest for assessing its antibacterial constituents. The n-hexane fraction of the crude acetone extract of the leaves exhibited antibacterial activity against Staphylococcus aureus. Isolation led to the known compounds cembratriene, (3 Z, 7 E, 11 Z)-15-hydroxycembra-3,7,11-trien-19-oic acid (1), the sesquiterpenoid, farnesal (2) and the viscidane diterpenoid, 5¦Á-hydroxyviscida-3,14-dien-20-oic acid (3). The purified compounds were tested for antibacterial activity with 2 and 3 showing moderate antibacterial activity against Gram-positive bacteria. View Full-Tex
%U https://www.mdpi.com/2079-6382/8/2/63