%0 Journal Article
%T Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients
%A Alexandre Evrard
%A Andr¨¦ P¨¨legrin
%A B¨¦r¨¦nice Framery
%A Fran£¿ois Scherninski
%A Fran£¿oise Cailler
%A J¨¦r£¿me Quinonero
%A Karen Dumas
%A Marian Gutowski
%A Nathalie Muller
%A Vincent Dubois
%J Archive of "Toxicology Reports".
%D 2019
%R 10.1016/j.toxrep.2019.04.011
%K FGS
%K fluorescence guided surgery
%K NIR
%K near infra-red
%K ICG
%K indocyanine green
%K CEA
%K carcinoembryonic antigen
%K mAb
%K monoclonal antibody
%K GLP
%K Good Laboratory Practices
%K PK
%K pharmacokinetics
%K AUC
%K Area Under the Curve
%K MTD
%K maximum tolerated dose
%K MRT
%K Mean Residence Time
%K NOAEL
%K no observable adverse effect level (NOAEL)
%K TMDD
%K target-mediated drug disposition Carcinoembryonic antigen
%K Cancer
%K Fluorescence guided surgery
%K Near-infrared fluorochrome
%K Toxicity
%K Pharmacokinetics
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506861/