%0 Journal Article
%T Biophysical and Biochemical Markers of Red Blood Cell Fragility
%A Ariel Orbach
%A Gregory Barshtein
%A Orly Zelig
%A Saul Yedgar
%J Archive of "Transfusion Medicine and Hemotherapy".
%D 2017
%R 10.1159/000452106
%X Red blood cells (RBCs) undergo a natural aging process occurring in the blood circulation throughout the RBC lifespan or during routine cold storage in the blood bank. The aging of RBCs is associated with the elevation of mechanical fragility (MF) or osmotic fragility (OF) of RBCs, which can lead to cell lysis. The present study was undertaken to identify RBC properties that characterize their susceptibility to destruction under osmotic/mechanical stress
%K Erythrocytes
%K Membrane defects
%K RBC aging
%K RBC lesion
%K RBC storage
%K Hemolysis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473068/