%0 Journal Article
%T Polymorphisms of VKORC1 and CYP2C9 are associated with warfarin sensitivity in Chinese population
%A Heng Cai
%A Jianlong Men
%A LiQun Jia
%A Minxin Wei
%A Zanxin Wang
%J Archive of "Therapeutics and Clinical Risk Management".
%D 2017
%R 10.2147/TCRM.S130198
%X Warfarin is a commonly prescribed anticoagulant for prevention of thromboembolic events. Wide inter-individual dose variation, narrow therapeutic range and risk of serious bleeding result in difficulties in achieving the therapeutic effect. The present study was designed to clarify the real biological significance of the polymorphisms of VKORC1 and cytochrome P450 2C9 (CYP2C9) in warfarin metabolism
%K warfarin
%K vitamin K
%K cytochrome P450
%K polymorphism
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384741/