%0 Journal Article %T About ATMPs, SOPs and GMP: The Hurdles to Produce Novel Skin Grafts for Clinical Use %A Daniela Marino %A Ernst Reichmann %J Archive of "Transfusion Medicine and Hemotherapy". %D 2016 %R 10.1159/000447645 %X The treatment of severe full-thickness skin defects represents a significant and common clinical problem worldwide. A bio-engineered autologous skin substitute would significantly reduce the problems observed with today's gold standard %K Bio-engineered skin grafts %K ATMP %K GMP %K Clinical trials %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073575/