%0 Journal Article
%T Differential impact of diabetes mellitus on antiplatelet effects of prasugrel and clopidogrel
%A Kazuomi Kario
%A Satoshi Niijima
%A Tsukasa Ohmori
%J Archive of "Thrombosis Journal".
%D 2018
%R 10.1186/s12959-017-0159-8
%X Study design at loading dose. Forty patients who were scheduled for percutaneous coronary intervention (PCI) under treatment with aspirin were randomized at admission to treatment of either a 20-mg loading dose (LD) of prasugrel or a 300-mg LD of clopidogrel. Platelet function analyses were performed at five time points (baseline, and 0.5, 3, 6, and 20 h) after the LD. Active metabolite concentrations were measured at 0.5 and 3 h after the L
%K Thienopyridines
%K P2Y12
%K Vasodilator-stimulated phosphoprotein phosphorylation
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853094/