%0 Journal Article
%T 18Fİ\fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of clinically nodeİ\negative nonİ\small cell lung cancer
%A Masafumi Kawamura
%A Noriyuki Matsutani
%A Shigeki Suzuki
%A Yusuke Takahashi
%J Archive of "Thoracic Cancer".
%D 2019
%R 10.1111/1759-7714.12978
%X One in four nonİ\small cell lung cancer (NSCLC) patients are diagnosed at an earlyİ\stage. Following the results of the National Lung Screening Trial that demonstrated a survival benefit for lowİ\dose computed tomography screening in highİ\risk patients, the incidence of earlyİ\stage NSCLC is expected to increase. Use of 18Fİ\fluorodeoxyglucose positron emission tomography/computed tomography during initial diagnosis of these earlyİ\stage lesions has been increasing. Traditionally, positron emission tomography/computed tomography scans have been utilized for mediastinal nodal staging and to rule out distant metastases in suspected earlyİ\stage NSCLC. In clinically nodeİ\negative NSCLC, the use of sublobar resection and selective lymph node dissection has been increasing as a therapeutic option. The higher rate of locoregional recurrences after limited resection and the significant incidence of occult lymph node metastases underscores the need to further stratify clinically nodeİ\negative NSCLC in order to select patients for limited resection versus lobectomy with complete mediastinal lymph node dissection. In this report, we review the published data, and discuss the significance and potential role of 18Fİ\fluorodeoxyglucose positron emission tomography/computed tomography evaluation for clinically nodeİ\negative NSCLC. Consequently, the literature review demonstrates that maximum standardized uptake value is a predictive factor for occult nodal metastasis with an accuracy of 55¨C77%. In addition, maximum standardized uptake value is a predictor for worse overall, as well as diseaseİ\free, survival
%K Earlyİ\stage
%K mediastinal nodal staging
%K occult lymph node metastasis
%K prognosis
%K standardized uptake value
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397908/