%0 Journal Article
%T Interaction of Platelet-Derived Microparticles with a Human B-Lymphoblast Cell Line: A Clue for the Immunologic Function of the Microparticles
%A Fatemah Yari
%A Mahboubeh Motefaker
%A Mahin Nikougoftar
%A Zahra Khayati
%J Archive of "Transfusion Medicine and Hemotherapy".
%D 2018
%R 10.1159/000479072
%X Platelets are blood cells with extensive capabilities in hemostasis. They also play a central role in the development of innate and adaptive immune responses. Little information exists about the immunostimulatory role of platelet-derived microparticles (Plt-MPs). To further elucidate this issue, we conducted this study using the B-lymphoblast cell line ¡®Daudi¡¯ as an available surrogate cell line for peripheral blood B lymphocytes. This cell line does not produce immunoglobulins (Igs) and has low expression of activation markers
%K Platelet microparticles
%K Daudi
%K CD27
%K CD86
%K IgG
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836167/