%0 Journal Article
%T Environmental insults: critical triggers for amyotrophic lateral sclerosis
%A Bing Yu
%A Roger Pamphlett
%J Archive of "Translational Neurodegeneration".
%D 2017
%R 10.1186/s40035-017-0087-3
%X Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by a rapid loss of lower and upper motor neurons. As a complex disease, the ageing process and complicated gene-environment interactions are involved in the majority of cases
%K Amyotrophic lateral sclerosis
%K Environmental risk factors
%K Mendelian randomisation
%K Mitochondrial dysfunction
%K Trigger
%K Initiation
%K Spread
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472994/