%0 Journal Article %T Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons %A Carlos Diaz-Montana %A Dominic Hague %A Lindsey Masters %A Louise Brown %A Mahesh K. B. Parmar %A Mary Rauchenberger %A Matthew R. Sydes %A Melissa Gannon %A Nadine Van Looy %A Nicholas James %A Stephen Townsend %A Tim Maughan %A for the STAMPEDE and FOCUS4 investigators %J Archive of "Trials". %D 2019 %R 10.1186/s13063-019-3322-7 %X The online version of this article (10.1186/s13063-019-3322-7) contains supplementary material, which is available to authorized users %K Adaptive trials %K Platform protocol %K Multi-arm multi-stage (MAMS) %K Trial conduct %K Data management %K Database %K Randomisation %K Case report form %K Methodology %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540437/